So you have to go beyond the magic of chemistry.
Spray the penetrant of your choice and let it sit overnite. Repeat.
On the water bottle bolts, what I would do is give them the treatment - whack 'em good, on top. Use a medium size hammer and a wood block. Impart a good mechanical shock into the thing (don't dent the tube). Consider the use of heat - but maybe not possible on a painted frame.
Then find a way to make the wrench absolutely secure on the bolt - again, use a wood block and a clamp or something so you have a good solid grip on the bolt.
Maybe at this point using a small hammer on the wrench to start it turning.
The point is - chemistry only gets you so far. After applying solvent, a little mechanical shock will break loose almost anything that's rusted.
Mark Petry
Bainbridge Island, WA